Study of People with Unexpected SADS Genetic Results

Did you get an unexpected genetic test result related to SADS?

A new NIH study is recruiting people who had genetic testing done for some other reason and got a result related to SADS. The goal is to learn more about how people use results like this. Please read below for more information about the study and thank you!

What is involved for people who join?

We want to know what you do about your result.

If you join the study, the first phase is a survey and phone interview. We will ask you about any changes you made to your healthcare based on the result. We will also ask if there were recommendations you did not follow and why. Finally, we will ask questions about sharing the result with your family members. You may be invited to the second phase of the study, which could include extra testing for you and/or your family members at the NIH or in your area. Being in the study and having testing done at the NIH is free. If we ask you to come to the NIH, and you live in the United States, we will pay for your travel and a hotel.

We provide a basic explanation of your result and may offer more.

You will get basic information about what your result means. You will also get a checklist of health actions you should take. You may get extra information, counseling or other support to get the healthcare that we recommend.

Help us improve care for future patients.

Results like yours are added to genetic testing reports with the hope that they will make families aware of important health risks so they can get the healthcare they need. We know that this does not happen for all families. We intend for our results to help more patients benefit from these results. For example, we hope to learn what makes it hard for patients to get care that they need and how healthcare providers can help.

Please partner with us.

Our study would not be possible without patients like you! Only 2 out of 100 people who have genetic testing get an unexpected result, so every patient is valuable to our project.

The Study is Open to People Who:

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Got a genetic testing result related to SADS after having genetic testing done for some other reason. This may include people (and parents of children) who have results related to one of these genes:

ACTC1 – DSC2 – DSG2 – DSP – GLA – KCNH2 – KCNQ1 – LMNA – MYBPC3 – MYH7 – MYL2 – MYL3 – PKP2 – PRKAG2 – RYR2 – SCN5A – TMEM43 – TNNI3 – TNNT2 – TPM1

If you have a result in another gene related to SADS, please contact us and we can decide if you can join the study.

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Speak English or Spanish

Common things that make someone ineligible for the study are:

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Having received genetic testing to get information about SADS risk

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Having a genetic result related to parentage or ancestry and not SADS

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Having a genetic result related to risk for Alzheimer’s disease and not SADS

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Having a genetic result related to cancer that is labelled on the laboratory report as a variant of uncertain significance

Study Contact Information

If you are interested, please contact us at [email protected], 301-402-6871, or https://www.surveymonkey.com/r/gsrpreferral

More information on this study